Umbrella have been working on a biological weapon called a “T-Virus” which infects everyone it comes into contact with turning them into zombies. Alice (Milla Jovovich) and team of mercenaries / operatives are charged with figuring out what’s going on.
Susan with her team of trekkers and guides go into Papua New Guinea to find her missing husband. They get a lot more than they bargained for having to avoid jungle animals and the cannibalistic natives.
Grace (played by Nicole Kidman) lives in a large mansion with her two kids. Things get darker as the children and deeply religious Grace are made aware something is going on in the house.